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ITS » Master Theses » Matematika - S2
Posted by dee@its.ac.id at 12/01/2012 10:41:47  •  142 Views

ANALISA STABILITAS MODEL MATEMATIKA DARI PERMASALAHAN STRATEGI PENGENDALIAN PENYEBARAN HUMAN IMMUNODEFICIENCY VIRUS TIPE GANAS DAN MUTAN MELALUI TERAPI INHIBITOR

ANALYSIS OF MATHEMATICAL MODEL STABILITY OF STRATEGY FOR CONTROLLING THE SPREAD OF HUMAN IMMUNODEFICIENCY VIRUS MALIGNANT AND MUTANT TYPE BY INHIBITOR THERAPY

Created by :
AFANDI, MUCHAMMAD ZAINUL  ( 1209201714 )



SubjectModel matematika
Virologi kedokteran
Alt. Subject Mathematical models
KeywordHIV / AIDS
Inhibitor Therapy
Optimal Control

[ Description ]

Puluhan juta orang telah terinfeksi Human Immunodeficiency Virus (HIV) sejak pertama kali ditemukan pada tahun 1980an, dan lebih dari dua puluh juta orang meninggal karena virus tersebut. Memang virus ini tidak menyebabkan kematian langsung pada penderita tetapi menginfeksi sel-sel kekebalan tubuh dari sistem kekebalan tubuh dan menyebabkan Acquired Immune Deficiency Syndrome (AIDS) sehingga melemahkan kemampuan sistem kekebalan untuk menangkal penyakit lain yang menyerang tubuh manusia. Dalam perkembangannya virus ini telah melahirkan generasi baru yang lebih ganas dan bermutasi, sehingga diperlukan penanganan tersendiri dalam mengatasinya. Salah satunya adalah dengan terapi inhibitor yang mencegah sel-sel terinfeksi HIV untuk mereplikasi dirinya sendiri. Dalam tesis ini menganalisa stabilitas model matematika dari permasalahan strategi pengendalian penyebaran HIV tipe ganas dan mutan melalui terapi inhibitor dengan periodisasi mingguan. Hasil simulasi menunjukkan bahwa semakin besar periodisasi yang diberikan, semakin menekan jumlah virus ganas dan mutan, serta semakin meningkatnya jumlah sel yang tidak terinfeksi. Selain itu, strategi periodisasi mingguan berdampak pada penghematan biaya.


Alt. Description

Tens of millions of people have been infected by human immunodeficiency virus (HIV) since it was first discovered in the 1980s, and more than twenty millions people died of the virus. Indeed, this virus does not cause direct mortality in patients but infects immune cells (T-helper) of the immune system and causes the Acquired Immune Deficiency Syndrome (AIDS) that weaken the immune system\\\\\\\\\\\\\\\'s ability to reject other illnesses that attack the human body. In the development of this virus has spawned a new generation of more malignant and mutating, thus requiring separate handling of the deal. One of them is by using a therapeutic inhibitor that prevents HIV-infected cells to replicate itself. This thesis analyzes mathematical model stability of strategy for controlling the spread of HIV malignant and mutant type using weekly inhibitor therapy. The simulation results show that the longer periodic makes virus population smaller, and the healthy cells grow well. Besides, weekly strategies impact to cost saving.

Contributor:
  1. Subchan, M.Sc., Ph.D.
Date Create:27/07/2011
Type:Text
Format:pdf
Language:Indonesian
Identifier:ITS-Master-3100011045190
Collection ID:3100011045190
Call Number:RTMa 511.8 Afa a


Source :
Master Thesis of Mathematics, RTMa 511.8 Afa a, 2011

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Copyright @2011 by ITS Library. This publication is protected by copyright and per obtained from the ITS Library prior to any prohibited reproduction, storage in a re transmission in any form or by any means, electronic, mechanical, photocopying, reco For information regarding permission(s), write to ITS Library

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  1.  ITS-Master-17206-1209201714-Cover_id.pdf - 211 KB pdf files
  2.  ITS-Master-17206-1209201714-Cover_en.pdf - 197 KB pdf files
  3.  ITS-Master-17206-1209201714-Approval_Sheet.pdf - 338 KB pdf files
  4.  ITS-Master-17206-1209201714-Abstract_id.pdf - 316 KB pdf files
  5.  ITS-Master-17206-1209201714-Abstract_en.pdf - 241 KB pdf files
  6.  ITS-Master-17206-1209201714-Preface.pdf - 359 KB pdf files
  7.  ITS-Master-17206-1209201714-Table_of_Content.pdf - 242 KB pdf files
  8.  ITS-Master-17206-1209201714-Illustrations.pdf - 244 KB pdf files
  9.  ITS-Master-17206-1209201714-Tables.pdf - 240 KB pdf files
  10.  ITS-Master-17206-1209201714-Enclosure_List.pdf - 239 KB pdf files
  11.  ITS-Master-17206-1209201714-Chapter1.pdf - 252 KB pdf files
  12.  ITS-Master-17206-1209201714-Conclusion.pdf - 244 KB pdf files
  13.  ITS-Master-17206-1209201714-Bibliography.pdf - 284 KB pdf files
  14.  ITS-Master-17206-1209201714-Biography.pdf - 242 KB pdf files
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  2. ITS-Master-17206-1209201714-Chapter3.pdf - 241 KB pdf files
  3. ITS-Master-17206-1209201714-Chapter4-1.pdf - 1148 KB pdf files
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  6. ITS-Master-17206-1209201714-Enclosure.pdf - 355 KB pdf files
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