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ITS » Undergraduate Theses » Biologi
Posted by fandikaaqsa@its.ac.id at 03/05/2016 14:56:27  •  671 Views


PENGARUH PEMBERIAN EKSTRAK IKAN GABUS CHANNA STRIATA PADA STRUKTUR HISTOLOGI HATI MENCIT MUS MUSCULUS HIPERGLIKEMIK

THE EFFECT OF SNAKE-HEAD FISH Channa striata EXTRACT ON LIVER HISTOLOGY STRUCTURE OF HYPERGLYCEMIC WHITE-MICE Mus musculus

Author :
NINGRUM, DWI INDAH LATIFAH ( 1510100045 )




ABSTRAK

Kondisi hiperglikemik dapat menyebabkan kerusakan jaringan hati. Pemberian albumin dapat meregenerasi jaringan hati. Ekstrak ikan gabus Channa striata banyak mengandung albumin sehingga dilakukan penelitian potensi ekstrak ikan gabus untuk meregenerasi jaringan hati mencit Mus musculus hiperglikemik. Hiperglikemik pada mencit diinduksi dengan aloksan dosis tunggal 190 mgkg berat badan secara intraperitoneal. Terapi menggunakan ekstrak ikan gabus dilakukan selama 14 hari dengan dosis bervariasi. Pengukuran kadar glukosa darah menggunakan glukometer Accu-Check Roche. Preparasi histologi hati mencit dengan metode irisan paraffin pewarnaan haematoxylin-eosin pengamatan dilakukan dengan mikroskop fotografi Olympus BX-41. Hasil penelitian menunjukkan bahwa terapi ekstrak ikan gabus dapat meregenerasi jaringan hati paling baik pada dosis 014846 mlhari dengan persentase perbaikan dari kondisi hiperglikemik sebesar 8056.


ABSTRACT

Hyperglycemic conditions can cause tissue damage in the heart. Albumin can regenerate tissue of liver. Snake-head fish Channa striata extract contain of albumines so that researched about potential of snake-head fish extract to regenerate tissue of liver of white-mice Mus musculus hyperglycemic. Hyperglycemic of white-mice induced by alloxan single dose of 190 mgkg body weight intraperitoneally. Therapy use snakehead fish extract conducted for 14 days with varying doses. Measurement of blood glucose level using glucometer of Roche Accu-Check. Preparation of white-mice liver histology with paraffin slices method staining with haematoxylin-eosin observations were made with a microscope photography of Olympus BX-41. The results showed that the fish extract cork therapy can regenerate liver tissue are best at doses 0.14846 ml day with the percentage improvement of hyperglycemic condition by 80.56.



KeywordsChanna striata; diabetes; glukosa darah; hat
 
Subject:  Ekstraksi (biologi)
Contributor
  1. Dra. Nurlita Abdulgani, M.Si
Date Create: 03/05/2016
Type: Text
Format: PDF
Language: Indonesian
Identifier: ITS-Undergraduate-15001160008762
Collection ID: 15001160008762
Call Number: RSBi 615.42 Nin p


Source
Undergraduate Thesis of Biology, RSBi 615.42 Nin p, 2014

Coverage
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Rights
Copyright @2016 by ITS Library. This publication is protected by copyright and per obtained from the ITS Library prior to any prohibited reproduction, storage in a re transmission in any form or by any means, electronic, mechanical, photocopying, reco For information regarding permission(s), write to ITS Library




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  1.  ITS-Undergraduate-41410-1510100045-abstract_id.pdf - 194 KB
  2.  ITS-Undergraduate-41410-1510100045-abstract_en.pdf - 195 KB
  3.  ITS-Undergraduate-41410-1510100045-conclusion.pdf - 475 KB




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