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ITS » Undergraduate Theses » Teknik Fisika S1
Posted by anisw@its.ac.id at 11/04/2016 10:40:26  •  1094 Views


SIMULASI MONTE CARLO UNTUK MENEMUKAN PENCIRI SPEKTRAL PENYAKIT DIABETES MELLITUS

MONTE CARLO SIMULATION TO FIND SPECTRAL FINGER-PRINTS OF DIABETES MELLITUS

Author :
ANSHORI, NASHRUDDIN ( 2409100040 )




ABSTRAK

Diagnosis penyakit diabetes mellitus adalah didasarkan atas kadar glukosa darah yang berbeda dari kondisi normal. Salah satu metode non-invasive dalam mengindentifikasi kadar glukosa darah adalah dengan menggunakan teknik Diffuse Reflectance Spectroscopy DRS. Ada dua pendekatan dalam DRS yaitu eksperimental dan komputasional. Pendekatan komputasional dilakukan dengan menggunakan algoritma Monte Carlo yang dianggap sebagai golden standard. Dalam studi komputasional ini disimulasikan pemodelan tissue kulit dan penjalaran cahaya didalamnya yang menggambarkan perilaku perubahan kadar glukosa darah 50 100 150 dan 200 mgdl serta ketebalan reticular dermis 01 03 dan 05 cm. Hasil simulasi menunjukkan bahwa sensitifitas perubahan nilai reflektansi terhadap perubahan kadar glukosa darah serta ketebalan reticular dermis yang terbesar terdapat pada tiga panjang gelombang terpilih secara berurutan adalah 645 820 dan 930 nm dan 765 845 dan 885 nm. Dapat disimpulkan bahwa tiga panjang gelombang tersebut adalah penciri spektral yang dapat digunakan untuk pengukuran yang sensitif dalam diagnostik penyakit diabetes mellitus.


ABSTRACT

Diagnostics of diabetes mellitus is based on blood glucose levels that are different from the one of normal condition. One of the methods of non-invasive blood glucose levels monitoring is using Diffuse Reflectance Spectroscopy DRS technique. There are two approaches in the DRS i.e. experimental and computational approaches. Computational approach is done using Monte Carlo method which is considered the golden standard. In this computational study the propagation of light in skin tissue model have been simulated which mimics the behavior of blood glucose level changes i.e. 50 100 150 and 200 mg dl as well as the thickness of the reticular dermis i.e. 0.1 0.3 and 0.5 cm. Results show that the triad wavelengths of 645 820 and 930 nm and 765 845 and 885 nm are the most sensitive to detect the changes in blood glucose levels and the reticular dermis thickness respectively. In conclusion the above three triads of wavelengths can thus being utilized as spectral finger-prints for sensitive measurements of the occurrence of diabetes mellitus in patients.



KeywordsDiabetes Mellitus; Non-Invasive; Diffuse Reflectance Spectoscopy; Monte Carlo; DRS.
 
Subject:  NOne
Contributor
  1. Dr.rer.nat. Ir. Aulia M. T. Nasution, M.Sc.
Date Create: 11/04/2016
Type: Text
Format: pdf
Language: Indonesian
Identifier: ITS-Undergraduate-24001160008626
Collection ID: 24001160008626
Call Number: RSF 618.924 62 Ans s


Source
Undergraduate Theses of Physics Engineering, RSF 618.924 62 Ans s, 2014

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Rights
Copyright @2016 by ITS Library. This publication is protected by copyright and per obtained from the ITS Library prior to any prohibited reproduction, storage in a re transmission in any form or by any means, electronic, mechanical, photocopying, reco For information regarding permission(s), write to ITS Library




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  1.  ITS-Undergraduate-41040-2409100040-abstract_id.pdf - 470 KB
  2.  ITS-Undergraduate-41040-2409100040-abstract_en.pdf - 429 KB
  3.  ITS-Undergraduate-41040-2409100040-conclusion.pdf - 355 KB




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